On a cross such as EUR/GBP held in a dollar account, the pip is first worth pounds, and pounds must then be converted to dollars. The chain is: pip size x units = value in quote-currency, then multiply by the quote currency's rate against your account-currency.
Getting this wrong is a common sizing error, because traders assume every pair is worth $10 per pip on a standard-lot. On sterling-quoted crosses it is higher; on yen-quoted crosses it moves with USD/JPY all day.
Example: 1 standard lot of EUR/GBP, GBP/USD at 1.2700. Pip value = 0.0001 x 100,000 = GBP 10, and GBP 10 x 1.2700 = USD 12.70 per pip. A 40-pip stop risks $508, not $400.
Related: pip-value, cross-rate